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Query by UniProt ID

Search degrons in proteomes of model organisms
H. sapiens, M. musculus, D. rerio, D. melanogaster, C. elegans, S. cerevisiae, A. thaliana

Query by sequence


Define own proteolytic sites (optional)
Define proteolytic sites to simulate cleavage and search for degrons in the newly emerged N-/C-terminus


Query by structure

Read about the recommended structure input here.
Define own proteolytic sites (optional)
Define proteolytic sites to simulate cleavage and search for degrons in the newly emerged N-/C-terminus



Customize parameters (optional; refers to any query type)

Read more about parameters here.

Primary degron-related
Degron flanking region in sequence [aa]
Degron flanking region in structure [Å]
Region length to calculate degron disorder [aa]

Secondary degron-related
Region length to calculate K/C/T/S disorder [aa]

Tertiary degron-related
Minimum IDR distance from K/C/T/S [aa]

Structure-related
Minimum continuous IDR length [aa]
pLDDT/LDDT disorder threshold [%]
Buried residue threshold [%]